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Qual Life Res. 2006 Sep;15(7):1179-90. Epub 2006 Sep 25.

Factor analysis techniques for assessing sufficient unidimensionality of cancer related fatigue.

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1
Center on Outcomes, Research and Education, Evanston Northwestern Healthcare and Northwestern University, 1001 University Place, Suite 100, 60201 Evanston, IL, USA. js-lai@northwestern.edu [corrected]

Erratum in

  • Qual Life Res. 2007 Jun;16(5):911.

Abstract

BACKGROUND:

Fatigue is the most common unrelieved symptom experienced by people with cancer. The purpose of this study was to examine whether cancer-related fatigue (CRF) can be summarized using a single score, that is, whether CRF is sufficiently unidimensional for measurement approaches that require or assume unidimensionality. We evaluated this question using factor analysis techniques including the theory-driven bi-factor model.

METHODS:

Five hundred and fifty five cancer patients from the Chicago metropolitan area completed a 72-item fatigue item bank, covering a range of fatigue-related concerns including intensity, frequency and interference with physical, mental, and social activities. Dimensionality was assessed using exploratory and confirmatory factor analysis (CFA) techniques.

RESULTS:

Exploratory factor analysis (EFA) techniques identified from 1 to 17 factors. The bi-factor model suggested that CRF was sufficiently unidimensional.

CONCLUSIONS:

CRF can be considered sufficiently unidimensional for applications that require unidimensionality. One such application, item response theory (IRT), will facilitate the development of short-form and computer-adaptive testing. This may further enable practical and accurate clinical assessment of CRF.

PMID:
17001438
DOI:
10.1007/s11136-006-0060-6
[Indexed for MEDLINE]
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