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Reprod Toxicol. 2006 Nov;22(4):578-9. Epub 2006 Jun 6.

The outcome of pregnancy following pre-pregnancy or early pregnancy alendronate treatment.

Author information

1
The Israeli Teratogen Information Service, Laboratory of Teratology, Hebrew University Hadassah Medical School, Israeli Ministry of Health, Jerusalem, Israel. ornoy@cc.huji.ac.il

Abstract

In spite of a substantial increase in the use of bisphosphonates at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 24 pregnancies after pre-pregnancy or early pregnancy alendronate therapy. Based on the pregnancy outcome it seems that alendronate does not impose a major teratogenic risk.

PMID:
16996245
DOI:
10.1016/j.reprotox.2006.05.009
[Indexed for MEDLINE]

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