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J Biomech Eng. 2006 Oct;128(5):742-50.

Myocardial material parameter estimation-a comparative study for simple shear.

Author information

1
Bioengineering Institute, University of Auckland, Auckland, New Zealand. h.schmid@auckland.ac.nz

Abstract

The study of ventricular mechanics-analyzing the distribution of strain and stress in myocardium throughout the cardiac cycle-is crucially dependent on the accuracy of the constitutive law chosen to represent the highly nonlinear and anisotropic properties of passive cardiac muscle. A number of such laws have been proposed and fitted to experimental measurements of stress-strain behavior. Here we examine five of these laws and compare them on the basis of (i) "goodness of fit:" How well they fit a set of six shear deformation tests, (ii) "determinability:" How well determined the objective function is at the optimal parameter fit, and (iii) "variability:" How well determined the material parameters are over the range of experiments. These criteria are utilized to discuss the advantages and disadvantages of the constitutive laws.

PMID:
16995761
DOI:
10.1115/1.2244576
[Indexed for MEDLINE]
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