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Physiology (Bethesda). 2006 Oct;21:362-9.

The mTOR pathway in the control of protein synthesis.

Author information

1
Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

Abstract

Signaling through mammalian target of rapamycin (mTOR) is activated by amino acids, insulin, and growth factors, and impaired by nutrient or energy deficiency. mTOR plays key roles in cell physiology. mTOR regulates numerous components involved in protein synthesis, including initiation and elongation factors, and the biogenesis of ribosomes themselves.

PMID:
16990457
DOI:
10.1152/physiol.00024.2006
[Indexed for MEDLINE]
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