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Infect Dis Clin North Am. 2006 Sep;20(3):711-27, viii.

Non-culture-based diagnostics for opportunistic fungi.

Author information

1
Department of Medical Microbiology, Radboud University, Nijmegen Medical Center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

Abstract

The value of the diagnostic markers galactomannan and 1,3-beta-D-glucan for the diagnosis of opportunistic fungal infections is reviewed in this article. Both markers have undergone clinical evaluation, and increasing insight is emerging with respect to the causes of false-negative or false-positive reactivity. These data will help design protocols in which single or multiple markers are used to identify patients who require antifungal therapy.

PMID:
16984877
DOI:
10.1016/j.idc.2006.06.009
[Indexed for MEDLINE]

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