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Neurosci Res. 2006 Nov;56(3):344-6. Epub 2006 Sep 18.

Cavum septi pellucidi and intrusive recollections in cancer survivors.

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1
Adult Mental Health Division, National Institute of Mental Health, National Center of Neurology and Psychiatry, Ogawahigashi 4-1-1, Kodaira, Tokyo 187-8553, Japan.

Abstract

A previous study reported abnormally large cavum septi pellucidi (CSP) in posttraumatic stress disorder (PTSD). We utilized magnetic resonance imaging to examine the frequency of large CSP, as defined by Nopoulos et al. (1997), in cancer survivors with and without intrusive recollections in a sample identical to that of our previous study. The frequency of large CSP did not differ between the two groups. The results suggest that alteration in midline structures during the course of neurodevelopment may lead to severe PTSD, while subthreshold PTSD, such as intrusive recollections, appear not to be associated with such alterations.

PMID:
16982105
DOI:
10.1016/j.neures.2006.07.011
[Indexed for MEDLINE]
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