Contraception for women with epilepsy

Epilepsia. 2006 Sep;47(9):1419-22. doi: 10.1111/j.1528-1167.2006.00671.x.

Abstract

Antiepileptic drugs that induce hepatic enzyme activity may alter the metabolism of most hormonal methods of contraception, and this affects the contraceptive regime. This effect should be considered in the choice of both the treatment of the epilepsy and the choice of contraceptive method. This review considers these interactions and offers advice about their management.

Publication types

  • Review

MeSH terms

  • Anticonvulsants / pharmacokinetics
  • Anticonvulsants / therapeutic use
  • Choice Behavior*
  • Contraception Behavior / psychology*
  • Contraceptive Agents, Female / administration & dosage*
  • Contraceptive Agents, Female / metabolism
  • Contraceptive Agents, Female / pharmacokinetics
  • Contraceptives, Oral, Hormonal / administration & dosage
  • Contraceptives, Oral, Hormonal / metabolism
  • Contraceptives, Oral, Hormonal / pharmacokinetics
  • Contraceptives, Postcoital, Hormonal / administration & dosage
  • Contraceptives, Postcoital, Hormonal / metabolism
  • Contraceptives, Postcoital, Hormonal / pharmacokinetics
  • Desogestrel / administration & dosage
  • Desogestrel / metabolism
  • Desogestrel / pharmacokinetics
  • Drug Interactions
  • Enzyme Induction / drug effects
  • Epilepsy / drug therapy*
  • Epilepsy / psychology*
  • Female
  • Humans
  • Intrauterine Devices
  • Liver / drug effects
  • Liver / enzymology
  • Medroxyprogesterone Acetate / administration & dosage
  • Medroxyprogesterone Acetate / metabolism

Substances

  • Anticonvulsants
  • Contraceptive Agents, Female
  • Contraceptives, Oral, Hormonal
  • Contraceptives, Postcoital, Hormonal
  • etonogestrel
  • Desogestrel
  • Medroxyprogesterone Acetate