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Brain Res. 1990 Jun 4;518(1-2):283-6.

Ethanol enhancement of GABA-activated chloride current in rat dorsal root ganglion neurons.

Author information

1
Department of Pharmacology, Northwestern University Medical School, Chicago, IL 60611.

Abstract

The acute effects of ethanol on the gamma-aminobutyric acid (GABA)-activated current were studied with the rat dorsal root ganglion neurons in primary culture using the whole-cell patch-clamp technique. GABA produced an inward chloride current, which was composed of an initial transient and a subsequent sustained phase. Ethanol at concentrations ranging from 30 to 300 mM enhanced the transient current in a concentration-dependent manner without affecting the sustained current.

PMID:
1697210
DOI:
10.1016/0006-8993(90)90982-h
[Indexed for MEDLINE]

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