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Trends Genet. 1990 Jul;6(7):223-7.

RNA metabolism: strategies for regulation in the heat shock response.

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Department of Molecular and Cell Biology, University of California, Berkeley 94720.


It has long been appreciated that selective transcription and translation play important roles in the heat shock response. More recently, regulatory strategies acting at the levels of RNA processing and message degradation have been shown to exert a profound effect on gene expression both during heat shock and during recovery from heat shock. In turn, as heat shock proteins accumulate, they affect those very processes that govern their expression.

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