dictyBase is the model organism database that houses all the sequence and associated data for Dictyostelium discoideum, including literature, researchers, and strains from the Dicty Stock Center. The database makes it possible to connect genes, proteins, and publications and is designed to address the needs of biologists and bioinformaticists alike. We provide tools for retrieving and analyzing data and strive to compile the highest quality, most up-to-date information. Here we will describe how to navigate the website and mine the extensive database to help users make optimal use of this invaluable resource.