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J Clin Microbiol. 2006 Sep;44(9):3381-3.

Peptide nucleic acid fluorescence in situ hybridization-based identification of Candida albicans and its impact on mortality and antifungal therapy costs.

Author information

1
Division of Infectious Diseases, University of Maryland School of Medicine, 20 Penn St., Rm. S403B, Baltimore, 21201, USA. gforrest@medicine.umaryland.edu

Abstract

The impact of rapid identification of Candida albicans blood isolates by peptide nucleic acid fluorescence in situ hybridization (PNA FISH) on the selection and expenditure of antifungal therapy was evaluated. PNA FISH was 100% sensitive and specific in the rapid identification of 31 out of 72 candidemias as C. albicans and resulted in a significant reduction of caspofungin usage, with an overall cost savings of 1,729 US dollars per patient.

PMID:
16954279
PMCID:
PMC1594692
DOI:
10.1128/JCM.00751-06
[Indexed for MEDLINE]
Free PMC Article

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