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Virol J. 2006 Sep 5;3:72.

Genetic analysis of Thailand hantavirus in Bandicota indica trapped in Thailand.

Author information

1
OSEB, UMR 5202 du CNRS, Muséum National d'Histoire naturelle, Paris, France. hugot@mnhn.fr

Abstract

Sixty one tissue samples from several rodent species trapped in five provinces of Thailand were examined for the presence of hantaviral markers by enzyme-immunoassay and immunoblotting. Four samples, all from the great bandicoot rat Bandicota indica, were confirmed positive for the hantaviral N-antigen. Two of them were trapped in Nakhon Pathom province, the other two in Nakhon Ratchasima province, approximately 250 km from the other trapping site. When analysed by RT-nested PCR, all four rodents were found positive for the hantaviral S- and M-segment nucleotide sequences. Genetic analysis revealed that the four newly described wild-type strains belong to Thailand hantavirus. On the phylogenetic trees they formed a well-supported cluster within the group of Murinae-associated hantaviruses and shared a recent common ancestor with Seoul virus.

PMID:
16953877
PMCID:
PMC1578555
DOI:
10.1186/1743-422X-3-72
[Indexed for MEDLINE]
Free PMC Article

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