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Virol J. 2006 Sep 4;3:71.

Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens.

Author information

1
CEH Oxford, Mansfield Road, Oxford OX1 3SR, UK. abuck@ceh.ac.uk

Abstract

We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within three weeks. During the following months, healthy chickens developed WNV neutralizing antibodies that were confirmed by immunoblotting and indirect immunofluorescence tests using WNV antigens. The proportion of seropositive chickens was higher for WNV than for Usutu virus or Sindbis virus. Attempts to isolate infectious virus or to detect viral RNA in the sera, failed.

PMID:
16952307
PMCID:
PMC1569371
DOI:
10.1186/1743-422X-3-71
[Indexed for MEDLINE]
Free PMC Article

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