Format

Send to

Choose Destination
Brain Res. 2006 Dec 18;1126(1):183-7. Epub 2006 Sep 1.

Dietary phytoestrogens enhance spatial memory and spine density in the hippocampus and prefrontal cortex of ovariectomized rats.

Author information

1
Department of Psychology, Hunter College of CUNY, 695 Park Ave., New York, NY 10021, USA. vluine@hunter.cuny.edu

Abstract

Long-term maintenance of ovariectomized rats (9 weeks) on chow containing high phytoestrogen levels (Purina LabDiet 5001) as compared to chow with minimal phytoestrogens (Harlan 2016 Teklad) was associated with better performance of the spatial memory task, object placement, increased dendritic spine density in CA1 and prefrontal cortex pyramidal neurons, and higher uterine weights. Object recognition memory, anxiety on an elevated plus maze and body weight were unaffected by phytoestrogen levels in the diet.

PMID:
16945354
DOI:
10.1016/j.brainres.2006.07.016
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center