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J Neurol. 2006 Aug;253 Suppl 4:IV2-7.

Early diagnosis of Parkinson's disease.

Author information

1
Dept. of Neurology, Saarland University, Kirrberger Strasse, 66421, Homburg/Saar, Germany. nejspi@uniklinik-saarland.de

Erratum in

  • J Neurol. 2008 Sep;255(9):1444.

Abstract

The clinical methods of olfactory testing and color discrimination as well as apparative methods such as transcranial ultrasound, dopamine transporter imaging and MIBG scintigraphy reveal a high sensitivity concerning the diagnosis of idiopathic Parkinson's disease (PD). The specificity of the presented methods, in particular of the dopamine transporter imaging--seems to be limited. All these methods and primarily their combination allow the detection of PD in early and--probably--preclinical stages. This requires sufficient therapeutic strategies to prevent and treat preclinical and early PD.

PMID:
16944352
DOI:
10.1007/s00415-006-4002-6
[Indexed for MEDLINE]

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