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J Am Coll Nutr. 2006 Aug;25(4):292-9.

Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review.

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Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging at Tufts University, Nutritional Epidemiology, Boston, MA 02111, USA.


Vitamin E consists of a group of eight isomers, four tocopherols (alpha-, beta-, gamma-, delta-tocopherol) and four tocotrienols (alpha-, beta-, gamma-, delta-tocotrienol). While extensive literature has been published on the potential health benefits of alpha-tocopherol, little is known about gamma-tocopherol, the major form of vitamin E in food in the U.S. gamma-tocopherol has recently received more research attention based on findings from in vitro and animal studies indicating that it has potent anti-inflammatory and antioxidant properties. Based on these recent studies, it is important to investigate the possible health benefits of gamma-tocopherol in humans. In this article, we review publications on dietary gamma-tocopherol intake, plasma gamma-tocopherol levels, cardiovascular disease and cancer risk in humans.

[Indexed for MEDLINE]

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