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Turk J Gastroenterol. 2006 Sep;17(3):206-8.

A prolonged gestational intrahepatic cholestasis: a case report.

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Department of Gastroenterology, Fatih University Hospital, Ankara, Turkey.


Gestational intrahepatic cholestasis, characterized by generalized pruritus and biochemical changes of cholestasis, usually occurs in the third trimester of pregnancy, persists until delivery and resolves spontaneously within the initial four weeks of the puerperium. The incidence is dependent on genetic basis, environmental factors and geographical location. We report the case of a patient with gestational intrahepatic cholestasis with an extraordinary clinical course that extended to the 82nd week postpartum.

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