Replicon typing of plasmids carrying CTX-M or CMY beta-lactamases circulating among Salmonella and Escherichia coli isolates

Katie L Hopkins; Ernesto Liebana; Laura Villa; Miranda Batchelor; E John Threlfall; Alessandra Carattoli

doi:10.1128/AAC.00149-06

Replicon typing of plasmids carrying CTX-M or CMY beta-lactamases circulating among Salmonella and Escherichia coli isolates

Antimicrob Agents Chemother. 2006 Sep;50(9):3203-6. doi: 10.1128/AAC.00149-06.

Authors

Katie L Hopkins¹, Ernesto Liebana, Laura Villa, Miranda Batchelor, E John Threlfall, Alessandra Carattoli

Affiliation

¹ Health Protection Agency Centre of Infections, London, UK.

Abstract

Replicon typing of plasmids carrying bla(CTX-M) or bla(CMY) beta-lactamase genes indicates a predominance of I1 and A/C replicons among bla(CMY)-carrying plasmids and five different plasmid scaffolds associated with the different types of bla(CTX-M) genes (I1, FII, HI2, K, and N). These results demonstrate the association of certain beta-lactamase genes with specific plasmid backbones.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cephalosporin Resistance
Conjugation, Genetic
Escherichia coli / enzymology
Escherichia coli / genetics*
Escherichia coli / isolation & purification
Plasmids / genetics*
Replicon / genetics*
Salmonella / enzymology
Salmonella / genetics*
Salmonella / isolation & purification
beta-Lactamases / genetics*
beta-Lactamases / metabolism

Substances

beta-lactamase CMY-2
beta-Lactamases