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Arch Virol. 1990;111(3-4):275-80.

In vitro isolation of a neutralization escape mutant of equine infectious anemia virus (EIAV).

Author information

1
Department of Veterinary Microbiology and Parasitology, Louisiana State University, School of Veterinary Medicine, Baton Rouge.

Abstract

A neutralization escape mutant (A/1 E) of equine infectious anemia virus was isolated after 13 passages in cell culture in the presence of serum containing antibodies to type- and group-specific determinants of EIAV envelope glycoproteins. Loss of neutralization by the selecting serum correlated with loss of two epitopes in the major envelope glycoprotein gp90 of A/1 E which were present in a parallel variant isolated from a persistently infected pony.

PMID:
1693846
DOI:
10.1007/bf01311062
[Indexed for MEDLINE]

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