TREKing toward new antidepressants

Nat Neurosci. 2006 Sep;9(9):1081-3. doi: 10.1038/nn0906-1081.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Antidepressive Agents / pharmacology
  • Behavior, Animal / drug effects
  • Depressive Disorder / genetics
  • Depressive Disorder / physiopathology*
  • Depressive Disorder / prevention & control
  • Fluoxetine / pharmacology
  • Gene Deletion*
  • Mice
  • Mice, Knockout
  • Potassium Channels, Tandem Pore Domain / deficiency
  • Potassium Channels, Tandem Pore Domain / genetics
  • Potassium Channels, Tandem Pore Domain / physiology*
  • Pyramidal Cells / drug effects
  • Pyramidal Cells / physiology

Substances

  • Antidepressive Agents
  • Potassium Channels, Tandem Pore Domain
  • potassium channel protein TREK-1
  • Fluoxetine