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Am J Kidney Dis. 2006 Sep;48(3):e27-9.

Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.

Author information

1
Department of Dermatology, Tuberous Sclerosis Center, Ludwig-Maximilian-University Munich, Gemany. ralf.wienecke@med.uni-muenchen.de

Abstract

A 19-year old patient with tuberous sclerosis presented with a renal angiomyolipoma. Because animal trials of tuberous sclerosis showed an effect of rapamycin on renal tumors, our patient was administered rapamycin for 6 months. During this time, the renal angiomyolipoma shrank significantly, regrew during an 8-month period, and decreased in size again after readministration of rapamycin.

PMID:
16931204
DOI:
10.1053/j.ajkd.2006.05.018
[Indexed for MEDLINE]

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