Format

Send to

Choose Destination
J Struct Biol. 2007 Jan;157(1):47-55. Epub 2006 Jul 16.

SPARX, a new environment for Cryo-EM image processing.

Author information

1
Lawrence Berkeley National Laboratory, Physical Bioscience Division, Berkeley, CA 94720, USA.

Abstract

SPARX (single particle analysis for resolution extension) is a new image processing environment with a particular emphasis on transmission electron microscopy (TEM) structure determination. It includes a graphical user interface that provides a complete graphical programming environment with a novel data/process-flow infrastructure, an extensive library of Python scripts that perform specific TEM-related computational tasks, and a core library of fundamental C++ image processing functions. In addition, SPARX relies on the EMAN2 library and cctbx, the open-source computational crystallography library from PHENIX. The design of the system is such that future inclusion of other image processing libraries is a straightforward task. The SPARX infrastructure intelligently handles retention of intermediate values, even those inside programming structures such as loops and function calls. SPARX and all dependencies are free for academic use and available with complete source.

PMID:
16931051
DOI:
10.1016/j.jsb.2006.07.003
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center