Format

Send to

Choose Destination
FEBS Lett. 2006 Sep 18;580(21):4996-5002. Epub 2006 Aug 17.

A novel salmonid myoD gene is distinctly regulated during development and probably arose by duplication after the genome tetraploidization.

Author information

1
Gatty Marine Laboratory, School of Biology, University of St Andrews, St Andrews, Fife, KY16 8LB Scotland, UK.

Erratum in

  • FEBS Lett. 2006 Nov 13;580(26):6286-7.

Abstract

A novel myoD paralogue was characterised in Salmo salar (smyoD1c) and S. trutta (btmyoD1c). SmyoD1c had 78.2/90.6% protein sequence identity to smyoD1a/smyoD1b, respectively. Each paralogue was differentially expressed throughout somitogenesis. In adult fish, smyoD1a was the predominant gene expressed in fast muscle, whereas smyoD1c was 2-3 times upregulated in slow muscle compared to smyoD1a/1b. A maximum likelihood analysis indicated that myoD1c arose by duplication of myoD1b after the salmonid tetraploidization. Another myoD paralogue (myoD2) is present in at least some teleosts, reflecting a more ancient genome duplication. To accommodate these findings we propose a simplified teleost-myoD nomenclature.

PMID:
16930594
DOI:
10.1016/j.febslet.2006.08.016
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center