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J Am Chem Soc. 2006 Aug 30;128(34):11008-9.

Encapsulation of single enzyme in nanogel with enhanced biocatalytic activity and stability.

Author information

1
Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.

Abstract

Single protein encapsulated into nanogels with uniformed size and controllable shell thickness were prepared by surface acryloylation of a protein molecule followed by aqueous in situ polymerization. Compared to its free counterpart, the encapsulated protein exhibits similar biocatalytic behavior and significantly improved stability at high temperature and in the presence of organic solvent.

PMID:
16925402
DOI:
10.1021/ja064126t
[Indexed for MEDLINE]

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