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Anal Bioanal Chem. 2006 Oct;386(3):506-14. Epub 2006 Aug 10.

Recent advances in methods for the analysis of catecholamines and their metabolites.

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1
Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. makotot@mol.f.u-tokyo.ac.jp

Abstract

Catecholamines, for example epinephrine, norepinephrine, and dopamine, are widely distributed and are important neurotransmitters and hormones in mammalian species. Several methods have been developed for analysis of catecholamines and related compounds. Determination of catecholamines in biological fluids has enabled us to clarify the physiological role played by these amines. Catecholamine levels in plasma and/or urine are also useful for diagnosis of several diseases, for example hypertension, pheochromocytoma, and neuroblastoma. This review covers reports from 2000 to the present of methods for the analysis of catecholamines and their metabolites.

PMID:
16924378
DOI:
10.1007/s00216-006-0675-z
[Indexed for MEDLINE]
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