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[Class III alcohol dehydrogenase and its role in the human body].

[Article in Polish]

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1
Zakład Diagnostyki Biochemicznej Akademii Medycznej w Białymstoku.

Abstract

Class III alcohol dehydrogenase is composed of two chi subunits, encoded by the ADH5 gene and existing in all tissues examined. It possesses a great ability to metabolize long-chain alcohols, while its capacity to oxidize ethanol is very limited. The amino-acid sequence homology and identical structural and kinetic properties indicate that class III alcohol dehydrogenase and formaldehyde dehydrogenase are identical enzymes. ADH III plays a significant role in the metabolism of formaldehyde in the human body.

PMID:
16921340
[Indexed for MEDLINE]
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