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Trends Neurosci. 2006 Oct;29(10):563-70. Epub 2006 Aug 21.

Lineage in the vertebrate retina.

Author information

1
Cellular Neurobiology Laboratory, Institut de Recherches Cliniques de Montréal (IRCM) and Université de Montréal, Montréal, Quebec H2W 1R7, Canada. michel.cayouette@ircm.qc.ca

Abstract

Recent results are changing the way we think about cell-fate decision mechanisms in the retina. For a long time it was accepted that lineage was not important in retinal cellular determination but, as we review here, new data show that lineage programmes might be at the heart of this process. These programmes are intrinsic, but they are also plastic and are influenced by extrinsic signals.

PMID:
16920202
DOI:
10.1016/j.tins.2006.08.003
[Indexed for MEDLINE]

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