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J Invest Dermatol. 2006 Sep;126(9):1931-2.

Non-pathogenic anti-desmoglein 3 IgG autoantibodies in Fogo Selvagem.

Author information

  • 1Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. amagai@sc.itc.keio.ac.jp

Abstract

The endemic form of pemphigus foliaceus, fogo selvagem, is caused by IgG autoantibodies directed against desmoglein 1 (Dsg1). Hilario-Vargas and his colleagues describe a high prevalence of IgG autoantibodies against Dsg3, the target antigen of pemphigus vulgaris, in a Brazilian population where fogo selvagem is endemic, although those patients do not develop any apparent clinical phenotype of pemphigus vulgaris.

PMID:
16912688
DOI:
10.1038/sj.jid.5700457
[PubMed - indexed for MEDLINE]
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