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Intern Med J. 2006 Sep;36(9):587-99.

Cautionary tales in the interpretation of systematic reviews of therapy trials.

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Department of Internal Medicine and Clinical Epidemiology, Princess Alexandra Hospital, University of Queensland, Brisbane, Queensland, Australia.


This is the second in a series of articles emphasizing the cautions in the interpretation of health-care studies. Systematic reviews are presented as comprehensive, unbiased summaries of evidence and are often referred to by clinicians, guideline developers and health policy-makers. Their strengths and limitations, and how their results can be subject to bias and misinterpretation, are discussed.

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