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J Clin Neurosci. 2006 Nov;13(9):965-8. Epub 2006 Aug 14.

Postoperative adjuvant treatment for pineal parenchymal tumour of intermediate differentiation.

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Department of Neurosurgery, Oita University, 1-1 Idaigaoka, Hasama, Oita 879 5593, Japan.


Pineal parenchymal tumour of intermediate differentiation (PPTID) in adults is rare and a treatment strategy for this condition has not yet been established. We present a case of an elderly patient treated with postoperative adjuvant therapy using radio- and chemotherapy. This 60-year-old man presented with a 3-month history of memory disturbance, gait instability and double vision. Computed tomography and magnetic resonance imaging demonstrated a mass in the pineal region that suggested a malignant tumour. Partial removal of the tumour was undertaken via the right occipital transtentorial approach. The histological diagnosis was PPTID. Postoperative radio- and chemotherapy were administered, with a good response. Little is known about the clinical behaviour of PPTID in adults. Our treatment plan indicates one effective option for the management of such tumours.

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