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Pediatr Nephrol. 2006 Nov;21(11):1765-8. Epub 2006 Aug 11.

ACE inhibition can improve orthostatic proteinuria associated with nutcracker syndrome.

Author information

1
Department of Pediatrics, Chungbuk National University Hospital, Gaesin-dong 62, Heungdeok-gu, Cheongju, Chungbuk, 361-240, South Korea. tsha@chungbuk.ac.kr

Abstract

Left renal vein entrapment syndrome (nutcracker syndrome) was documented by magnetic resonance angiography (MRA) as a cause of orthostatic proteinuria in a 14-year-old girl female adolescent. Because of continuous proteinuria we performed a left renal biopsy which showed moderate mesangial hypercellularity. Her overt orthostatic proteinuria disappeared after a treatment of angiotensin-converting enzyme (ACE) inhibition. Nutcracker syndrome remains a rare but important cause of elevated protein excretion, which can induce mesangial changes and be improved by ACE inhibitor treatment.

PMID:
16902785
DOI:
10.1007/s00467-006-0206-3
[Indexed for MEDLINE]

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