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Cell. 2006 Aug 11;126(3):435-9.

Rough sheets and smooth tubules.

Author information

1
Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

Abstract

The endoplasmic reticulum (ER) has distinct morphological domains composed of sheets and tubules, which differ in their characteristic membrane curvature. Key proteins may drive the formation of these structural morphologies, which in turn could generate the rough and smooth functional domains of the ER.

PMID:
16901774
DOI:
10.1016/j.cell.2006.07.019
[Indexed for MEDLINE]
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