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Korean J Ophthalmol. 2006 Jun;20(2):99-103.

Triamcinolone-induced intraocular pressure elevation: intravitreal injection for macular edema and posterior subtenon injection for uveitis.

Author information

1
Department of Ophthalmology, College of Medicine, Pusan National University, Busan, Korea. jea-sy@hanmail.net

Abstract

PURPOSE:

To assess the effect of intravitreal and posterior subtenon injections of triamcinolone acetonide (TA) on intraocular pressure (IOP).

METHODS:

we reviewed 42 consecutive eyes after intravitreal TA injection (IVTA) and 43 eyes following posterior subtenon TA injection (PSTA). All cases had a minimum follow-up time of three months. After injection, the value and time of the maximal IOP, the amount of IOP elevation and the needs of the medication were assessed.

RESULTS:

The lOP increased significantly (p < 0.001) from 16.3 +/- 2.5 mmHg preoperatively to a mean maximum of 21.7 +/- 5.3 mmHg in the IVTA group, and from 15.3 +/- 4.5 mmHg to 20.6 +/- 3.0 mmHg in the PSTA group. An elevation in the IOP of more than 5 mmHg from the baseline lOP was seen in 52.4% of the IVTA group at a mean time of 3.1 weeks postoperatively, and 44.2% of the PSTA group displayed an IOP elevation at 5.9 weeks.

CONCLUSIONS:

Both developed significant elevations of IOP, but this appeared at a later date in the PSTA group. Careful follow-up after local injection of steroids is necessary.

PMID:
16892645
PMCID:
PMC2908835
DOI:
10.3341/kjo.2006.20.2.99
[Indexed for MEDLINE]
Free PMC Article

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