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Acta Otorhinolaryngol Ital. 2006 Apr;26(2):118-20; discussion 120.

Extramedullary plasmacytoma of paranasal sinuses. A combined therapeutic strategy.

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Department of Neurology and Otolaryngology, University La Sapienza, Rome, Italy.


Extramedullary plasmacytoma of the head and neck region is a rare malignant tumour comprising approximately 3% of all plasma cell tumours. Approximately 80-90% of extramedullary plasmacytomas involve the Mucosa-Associated Lymphoid Tissue of the upper airways, 75% of these involve the nasal and paranasal regions. Radiotherapy is considered the treatment of choice, surgery being limited to biopsy and to excision of residual disease. A case of extramedullary plasmacytoma of the nasal cavity and ethmoid sinus is reported, in which surgical excision is followed by complementary radiotherapy on the site of the tumour.

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