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Anticancer Res. 2006 Jul-Aug;26(4B):3057-63.

An in vivo analysis of the herbal compound essiac.

Author information

1
Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Abstract

BACKGROUND:

Essiac is a herbal compound that has been in common use with cancer patients in North America for over 80 years. Despite its relatively widespread use, there are no peer-reviewed published reports of in vivo studies regarding the use of this compound.

MATERIALS AND METHODS:

Essiac was administered orally to test animals prior to all experiments. Standard assays to test protection from ethanol-induced gastric ulceration and carbon tetrachloride-induced hepatic injury were performed on Wistar rats. Assays of postglucose-load serum glucose and cellular and humoral immune modulation were conducted on ICR and BALB/C mice, respectively.

RESULTS:

Essiac demonstrated a modest gastric protective effect via reduction of ethanol-induced gastric ulceration. However, Essiac did not demonstrate significant hepatoprotective, hypoglycemic or immunomodulatory properties.

CONCLUSION:

Essiac, administered in established in vivo experimental models, did not significantly demonstrate its purported physiological modifying effects.

PMID:
16886634
[Indexed for MEDLINE]
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