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Curr Opin Genet Dev. 1991 Oct;1(3):313-8.

Biogenesis of the bacterial pilus.

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Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.


The assembly of surface structures in gram-negative bacteria requires specialized secretion and chaperone systems localized on both sides of the cytoplasmic membrane. Major advances have been made over the last year in understanding how these systems form part of a general strategy used by bacteria to cap and target interactive subunits imported into the periplasmic space to outer membrane uncapping and assembly sites.

[Indexed for MEDLINE]

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