Format

Send to

Choose Destination
Cell. 2006 Jul 28;126(2):237-9.

Have you HRD? Understanding ERAD is DOAble!

Author information

1
Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore 117604.

Abstract

Numerous factors are involved in the eradication of misfolded proteins, yet how these factors achieve substrate specificity remains unclear. In this issue of Cell, Denic et al. (2006) and Carvalho et al. (2006) report that two distinct protein complexes at the endoplasmic reticulum membrane are responsible for the recognition and degradation of specific subsets of protein substrates.

PMID:
16873052
DOI:
10.1016/j.cell.2006.07.001
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center