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Cell. 2006 Jul 28;126(2):231-5.

Knocking down disease with siRNAs.

Author information

1
CBR Institute for Biomedical Research and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Knocking down expression of disease-related genes using small interfering RNAs (siRNAs) has potential for treating a variety of illnesses. This Essay will examine the opportunities for harnessing RNA interference (RNAi) for therapy, as well as the obstacles and possible ways to circumvent them.

PMID:
16873051
DOI:
10.1016/j.cell.2006.07.007
[Indexed for MEDLINE]
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