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Child Psychiatry Hum Dev. 1991 Winter;22(2):79-87.

Cognitive effects of psychostimulant medication in hyperactive children.

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Ecole de Psychologie, Université Laval Ste Foy, Québec, Canada.


Hyperactive and normal children were given a test of selective attention (Stroop test) and a neurocognitive test sensitive to a functional deficit of prefrontal cortex (Wisconsin Card Sorting Test). Hyperactive children showed significant deficits on both measures. After a year of psychostimulant medication, the hyperactive children all showed clinical and neurocognitive improvement, but continued to show a selective attention deficit compared with normal children. The results indicate a dissociation between the cognitive processes measured by the Wisconsin test and selective attention as measured by the Stroop, and that the selective attention deficit is more resistant to psychostimulant intervention.

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