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Immunol Today. 1991 Dec;12(12):429-31.

Modulation of MHC antigen expression by viruses and oncogenes.

Author information

1
Dept of Biological Sciences, University of Warwick, Coventry, UK.

Abstract

It is becoming increasingly clear that regulation of MHC antigen expression by viruses and oncogenes, leading to either immune evasion or autoimmunity, is widespread and important in disease. At a recent meeting*, which brought together workers interested in tumour immunology, viral infection and the MHC, a number of mechanisms for the regulation of MHC antigen expression were revealed and the importance of balanced expression of MHC gene products to effective immunity was underlined.

PMID:
1686171
DOI:
10.1016/0167-5699(91)90013-J
[Indexed for MEDLINE]

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