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Int J Neurosci. 2006 Aug;116(8):881-94.

Schizophrenia and red light: fMRI evidence for a novel biobehavioral marker.

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Psychology Department, University of Central Florida, Orlando, 32816, USA.


Previous research has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual pathway. An earlier psychophysical study found that a subset of nonpsychotic relatives of persons with schizophrenia showed the opposite effect when compared to healthy adults (Bedwell et al., 2003), suggesting a novel biobehavioral marker for the disorder. The present study attempted to replicate and explore the mechanism for this effect using fMRI. Results provide physiological evidence that the M pathway response to red light is in the opposite direction than expected in a subset of nonpsychotic relatives of persons with schizophrenia.

[Indexed for MEDLINE]

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