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Int J Neurosci. 2006 Aug;116(8):881-94.

Schizophrenia and red light: fMRI evidence for a novel biobehavioral marker.

Author information

1
Psychology Department, University of Central Florida, Orlando, 32816, USA. jbedwell@mail.ucf.edu

Abstract

Previous research has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual pathway. An earlier psychophysical study found that a subset of nonpsychotic relatives of persons with schizophrenia showed the opposite effect when compared to healthy adults (Bedwell et al., 2003), suggesting a novel biobehavioral marker for the disorder. The present study attempted to replicate and explore the mechanism for this effect using fMRI. Results provide physiological evidence that the M pathway response to red light is in the opposite direction than expected in a subset of nonpsychotic relatives of persons with schizophrenia.

PMID:
16861153
DOI:
10.1080/00207450500516529
[Indexed for MEDLINE]

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