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J Pediatr. 2006 Jul;149(1):125-7.

Pediatric multiple sclerosis: detection of clinically silent lesions by multimodal evoked potentials.

Author information

1
Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Germany. dpohl@med.uni-goettingen.de

Abstract

Pediatric patients with multiple sclerosis (MS) frequently do not meet MRI criteria for diagnosis because of lack of evidence of dissemination in space. We assessed the diagnostic utility of multimodal evoked potentials (EP). In 46% of 85 childhood patients with MS, spatial dissemination was detected by EP before the second clinical attack. EP may constitute an important tool for earlier diagnosis of pediatric MS.

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PMID:
16860140
DOI:
10.1016/j.jpeds.2006.01.003
[Indexed for MEDLINE]

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