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Acta Derm Venereol. 1991;71(6):518-24.

Common and dysplastic naevi as risk factors for cutaneous malignant melanoma in a Swedish population.

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1
Department of Dermatology, Sahlgrenska Hospital, Göteborg, Sweden.

Abstract

Common naevi, dysplastic naevi (DN) and other phenotypic features were evaluated as melanoma risk factors in a Swedish case-control study. One-hundred and twenty-one prevalent melanoma cases and 378 randomly selected controls participated. The mean total body naevus count was 115 in the cases and 67 in the controls. Fifty-six per cent of the cases and 18% of the controls had clinical DN. The corresponding figures for histologically diagnosed DN were 40% and 8% respectively. Clinical DN was as good as histologically diagnosed DN in identifying individuals at risk for melanoma. Subjects with sun-sensitive skin, greater than or equal to 150 naevi and presence of DN have 50 times higher melanoma risk than those without these characteristics.

PMID:
1685835
[Indexed for MEDLINE]
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