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J Dermatolog Treat. 2006;17(3):176-8.

Secondary cutaneous effects of hydroxyurea: possible pathogenetic mechanisms.

Author information

1
Di.S.E.M. Department of Endocrinological and Metabolic Science, Section of Dermatology, University of Genoa, Genoa, Italy.

Abstract

We report the case of a 73-year-old man who had been on hydroxyurea for essential thrombocythemia since 1988. After 12 years of treatment he developed a symmetrical dermatomyositis-like eruption together with a leg ulceration and five squamous cell carcinomas of the face. The possible pathogenetic mechanisms of these known side effects are discussed.

PMID:
16854761
DOI:
10.1080/09546630600780494
[Indexed for MEDLINE]

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