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Res Microbiol. 2006 Oct;157(8):701-13. Epub 2006 Jun 30.

Biological roles of the Lon ATP-dependent protease.

Author information

1
Laboratoire de Génétique des Procaryotes, IBMM, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, 6041 Gosselies, Belgium.

Abstract

The Lon ATP-dependent protease plays a major role in protein quality control. An increasing number of regulatory proteins, however, are being identified as Lon substrates, thus indicating that in addition to its housekeeping function, Lon plays an important role in regulating many biological processes in bacteria. This review presents and discusses the involvement of Lon in different aspects of bacterial physiology, including cell differentiation, sporulation, pathogenicity and survival under starvation conditions.

PMID:
16854568
DOI:
10.1016/j.resmic.2006.05.004
[Indexed for MEDLINE]

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