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Br J Surg. 2006 Aug;93(8):921-8.

Systematic review of laparoscopic versus open surgery for colorectal cancer.

Author information

1
Unidad de Evaluación de Tecnologías Sanitarias, Agencia Laín Entralgo, Consejería de Sanidad y Consumo, Madrid, Spain. mercedes.reza@salud.madrid.org

Abstract

BACKGROUND:

This study compares the efficacy and safety of laparoscopic surgery (LS) and open surgery (OS) for colorectal cancer.

METHODS:

An electronic search of the literature was undertaken to identify primary studies and systematic reviews. Information on the efficacy and safety of LS versus OS was analysed. A meta-analysis was conducted to examine long-term outcomes.

RESULTS:

A systematic review published in 2000 and 12 more recent randomized clinical trials were identified. Compared with OS, LS reduced blood loss and pain, and resulted in a faster return of bowel function and earlier resumption of normal diet. Hospital stay was up to 2 days shorter after LS. No significant differences between the techniques were noted in the incidence of complications or postoperative mortality. The time required to complete LS was significantly longer (0.5-1.0 h more). No significant differences were found between the two procedures in terms of overall mortality, cancer-related mortality or disease recurrence.

CONCLUSION:

LS takes longer than OS but offers several short-term benefits. However, complication rates are similar for both procedures and no differences were found in long-term outcomes.

PMID:
16845692
DOI:
10.1002/bjs.5430
[Indexed for MEDLINE]

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