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Cell. 2006 Jul 14;126(1):25-7.

Heterotrimeric G protein signaling: Getting inside the cell.

Author information

1
Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520, USA. michael.koelle@yale.edu

Abstract

Heterotrimeric G proteins have traditionally been thought to transduce signals at the plasma membrane. In this issue, Slessareva et al. (2006) now show that a G protein alpha subunit acts at the endosome to stimulate a phosphatidylinositol 3-kinase to help yeast respond to mating pheromones.

PMID:
16839871
DOI:
10.1016/j.cell.2006.06.026
[Indexed for MEDLINE]
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