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Cell. 2006 Jul 14;126(1):19-22.

Flipping riboswitches.

Author information

1
Department of Biochemistry, New York University School of Medicine, New York, NY 10016, USA. evgeny.nudler@med.nyu.edu

Abstract

Riboswitches are common cis-acting regulatory elements in bacteria. They are made of nascent RNA that changes its conformation in response to direct binding of cognate metabolites. The publication of five high-resolution crystal structures provides a comprehensive view of how riboswitches sense their ligands and points to new challenges in this emerging field.

PMID:
16839869
DOI:
10.1016/j.cell.2006.06.024
[Indexed for MEDLINE]
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