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Kidney Int. 2006 Jul;70(2):238-40.

Hepatocyte growth factor: new arsenal in the fights against renal fibrosis?

Author information

1
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA. liuy@upmc.edu

Abstract

Hepatocyte growth factor (HGF) has emerged as a potent, endogenous antifibrotic factor that shows an impressive efficacy in ameliorating tissue fibrosis in a wide variety of animal models. Herrero-Fresneda et al. provide new evidence demonstrating that intramuscular injection of HGF gene reduces mortality, inflammation, and renal fibrosis in chronic allograft nephropathy.

PMID:
16838037
DOI:
10.1038/sj.ki.5001661
[Indexed for MEDLINE]
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