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Acta Psychiatr Scand. 2006 Aug;114(2):109-17.

Randomized controlled trial of a cannabis-focused intervention for young people with first-episode psychosis.

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  • 1Early Psychosis Prevention and Intervention Centre/ORYGEN Youth Health, Parkville, Vic., Australia.



To evaluate a cannabis-focused intervention (cannabis and psychosis therapy: CAP) for patients continuing to use cannabis following initial treatment for first-episode psychosis (FEP).


Consecutive admissions to an early psychosis program were screened and consenting individuals using cannabis in the 4 weeks prior to assessment participated. A single-blind randomized controlled trial compared CAP (n = 23) with a clinical control condition (psychoeducation, PE; n = 24). There were no significant differences between the CAP and PE groups on cannabis use at end of treatment and 6 months post-intervention.


There were no significant group differences on psychopathology and functional ratings at follow-up. A significant reduction in cannabis use was observed for both groups over time.


PE and specific cannabis-focused intervention are associated with similar reductions in cannabis use in an FEP cohort. Simple interventions may therefore be worth considering prior to intensive psychotherapeutic efforts with this population.

[PubMed - indexed for MEDLINE]
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